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    Resultados: 4

    The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance

    World Health Organization.
    This document provides a summary of the evidence and recommendations for the use of SL-LPA for the detection of mutations associated with resistance to fluoroquinolones and SLID in patients with RR-TB and/or MDR-TB. The objectives of this policy guidance are to assess and compare the diagnostic accuracy ...
    Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico, Antibióticos Antituberculosos/farmacología, Técnicas de Sonda Molecular, Pruebas de Sensibilidad Microbiana, Fluoroquinolonas/uso terapéutico, Farmacorresistencia Bacteriana/genética, Genotipo, Mutación, Tuberculosis Resistente a Múltiples Medicamentos/genética, Mycobacterium tuberculosis/efectos de los fármacos, Mycobacterium tuberculosis/genética
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    The use of molecular line probe assays for the detection of resistance to isoniazid and rifampicin

    World Health Organization.
    Tuberculosis (TB) remains a large-scale public health problem. Key global priorities for TB care and control include improving case-detection and detecting cases earlier, including cases of smear-negative disease. This document updates existing WHO policy on the use of molecular LPAs for detecting MTBC a...
    Técnicas de Sonda Molecular, Rifamicinas/uso terapéutico, Isoniazida/uso terapéutico, Tuberculosis Resistente a Múltiples Medicamentos/diagnóstico, Antituberculosos/uso terapéutico, Isoniazida/farmacología, Rifampin/farmacología, Mycobacterium tuberculosis/efectos de los fármacos, Farmacorresistencia Bacteriana, Reproducibilidad de los Resultados
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    The use of delamanid in the treatment of multidrug-resistant tuberculosis in children and adolescents: interim policy guidance

    World Health Organization.
    The specific objectives were to evaluate the harms to benefits ratio of delamanid in combination with the currently recommended MDR-TB treatment regimen in children. Based on this evaluation, to develop recommendations on the use of delamanid as part of WHO-recommended longer MDR-TB treatment regimens, a...
    Tuberculosis Resistente a Múltiples Medicamentos/tratamiento farmacológico, Antibióticos Antituberculosos/administración & dosificación, Resultado del Tratamiento, Nitroimidazoles/administración & dosificación
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    WHO treatment guidelines for drug-resistant tuberculosis, 2016 update

    World Health Organization.
    In November 2015, the World Health Organization (WHO) convened a meeting of a Guideline Development Group (GDG) for the update of policy recommendations on the treatment of drug-resistant TB. The GDG was composed of a multidisciplinary group of tuberculosis (TB) and drug-resistant TB experts external to ...
    Tuberculosis Resistente a Múltiples Medicamentos/tratamiento farmacológico, Antituberculosos/uso terapéutico, Tuberculosis/tratamiento farmacológico
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